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Maximum entropy and population heterogeneity in continuous cell cultures
Continuous cultures of mammalian cells are complex systems displaying hallmark phenomena of nonlinear dynamics, such as multi-stability, hysteresis, as well as sharp transitions between different metabolic states. In this context mathematical models may suggest control strategies to steer the system...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411232/ https://www.ncbi.nlm.nih.gov/pubmed/30811392 http://dx.doi.org/10.1371/journal.pcbi.1006823 |