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Clinical utility of tafenoquine in the prevention of relapse of Plasmodium vivax malaria: a review on the mode of action and emerging trial data

Tafenoquine is an 8-aminoquinoline with activity against all human life cycle stages of Plasmodium vivax, including dormant liver stages – so called hypnozoites. Its long half-life of ~15 days is allowing for a single exposure regimen. It has been under development since 1980 and received approval b...

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Detalles Bibliográficos
Autores principales: Hounkpatin, Aurore B, Kreidenweiss, Andrea, Held, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411314/
https://www.ncbi.nlm.nih.gov/pubmed/30881061
http://dx.doi.org/10.2147/IDR.S151031