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CGK062, a small chemical molecule, inhibits cancer upregulated gene 2-induced oncogenesis through NEK2 and β-catenin

The mechanisms through which cancer-upregulated gene 2 (CUG2), a novel oncogene, affects Wnt/β-catenin signaling, essential for tumorigenesis, are unclear. In this study, we aimed to elucidate some of these mechanisms in A549 lung cancer cells. Under the overexpression of CUG2, the protein levels an...

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Detalles Bibliográficos
Autores principales: Kaowinn, Sirichat, Oh, Sangtaek, Moon, Jeong, Yoo, Ah Young, Kang, Ho Young, Lee, Mi Rim, Kim, Ji Eun, Hwang, Dae Youn, Youn, So Eun, Koh, Sang Seok, Chung, Young-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411349/
https://www.ncbi.nlm.nih.gov/pubmed/30968157
http://dx.doi.org/10.3892/ijo.2019.4724