Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling

Metformin is commonly used to treat patients with type 2 diabetes and is associated with a decreased risk of cancer. Previous studies have demonstrated that metformin can act alone or in synergy with certain anticancer agents to achieve anti-neoplastic effects on various types of tumors via adenosin...

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Detalles Bibliográficos
Autores principales: Lu, Chi-Cheng, Chiang, Jo-Hua, Tsai, Fuu-Jen, Hsu, Yuan-Man, Juan, Yu-Ning, Yang, Jai-Sing, Chiu, Hong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411354/
https://www.ncbi.nlm.nih.gov/pubmed/30720062
http://dx.doi.org/10.3892/ijo.2019.4704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411354/
https://www.ncbi.nlm.nih.gov/pubmed/30720062
http://dx.doi.org/10.3892/ijo.2019.4704

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