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Women’s cancers: how the discovery of BRCA genes is driving current concepts of cancer biology and therapeutics
Over the last two decades, discoveries related to the breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2) have profoundly changed our understanding and management of hereditary breast and ovarian cancers. The concept of synthetic lethality, which arises when cells become vulnerable to a com...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cancer Intelligence
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411414/ https://www.ncbi.nlm.nih.gov/pubmed/30915162 http://dx.doi.org/10.3332/ecancer.2019.904 |