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Transmissible ER Stress Reconfigures the AML Bone Marrow Compartment

Successive adaptation of the bone marrow (BM) from homeostatic hematopoietic microenvironment to a self-reinforcing niche is an integral aspect of leukemogenesis. Yet, the cellular mechanisms underlying these functional alterations remain to be defined. Here, we found that AML incursion precipitates...

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Detalles Bibliográficos
Autores principales: Doron, Ben, Abdelhamed, Sherif, Butler, John T., Hashmi, Saman K., Horton, Terzah M., Kurre, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411460/
https://www.ncbi.nlm.nih.gov/pubmed/30206307
http://dx.doi.org/10.1038/s41375-018-0254-2