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Androgen receptor expression reduces stemness characteristics of prostate cancer cells (PC3) by repression of CD44 and SOX2

Studies have shown that a subgroup of tumor cells possess stemness characteristics having self‐renewal capacity and the ability to form new tumors. We sought to identify the plausible stemness factor that determines the “molecular signature” of prostate cancer (PCa) cells derived from different meta...

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Detalles Bibliográficos
Autores principales: Srinivasan, Deepa, Senbanjo, Linda, Majumdar, Sunipa, Franklin, Renty B., Chellaiah, Meenakshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411465/
https://www.ncbi.nlm.nih.gov/pubmed/30206982
http://dx.doi.org/10.1002/jcb.27573