Applying surface-based hippocampal morphometry to study APOE-E4 allele dose effects in cognitively unimpaired subjects

Apolipoprotein E (APOE) e4 is the major genetic risk factor for late-onset Alzheimer's disease (AD). The dose-dependent impact of this allele on hippocampal volumes has been documented, but its influence on general hippocampal morphology in cognitively unimpaired individuals is still elusive. C...

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Detalles Bibliográficos
Autores principales: Dong, Qunxi, Zhang, Wen, Wu, Jianfeng, Li, Bolun, Schron, Emily H., McMahon, Travis, Shi, Jie, Gutman, Boris A., Chen, Kewei, Baxter, Leslie C., Thompson, Paul M., Reiman, Eric M., Caselli, Richard J., Wang, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411498/
https://www.ncbi.nlm.nih.gov/pubmed/30852398
http://dx.doi.org/10.1016/j.nicl.2019.101744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411498/
https://www.ncbi.nlm.nih.gov/pubmed/30852398
http://dx.doi.org/10.1016/j.nicl.2019.101744

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