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Cerebrospinal fluid biomarkers of neurofibrillary tangles and synaptic dysfunction are associated with longitudinal decline in white matter connectivity: A multi-resolution graph analysis

In addition to the development of beta amyloid plaques and neurofibrillary tangles, Alzheimer's disease (AD) involves the loss of connecting structures including degeneration of myelinated axons and synaptic connections. However, the extent to which white matter tracts change longitudinally, pa...

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Detalles Bibliográficos
Autores principales: Kim, Won Hwa, Racine, Annie M., Adluru, Nagesh, Hwang, Seong Jae, Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Asthana, Sanjay, Koscik, Rebecca L., Johnson, Sterling C., Bendlin, Barbara B., Singh, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411581/
https://www.ncbi.nlm.nih.gov/pubmed/30502079
http://dx.doi.org/10.1016/j.nicl.2018.10.024