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Matrix Metalloprotease Generated Fragments of Type VI Collagen Have Serum Biomarker Potential in Cancer – A Proof of Concept Study

BACKGROUND: Type VI collagen (COL6) is associated with several pro-tumorigenic events. COL6 is primarily composed of three alpha-chains (a1-a3) forming a specialized microfibrillar network to support tissue architecture. COL6 homeostasis is lost in the tumor due to increased COL6 synthesis by activa...

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Detalles Bibliográficos
Autores principales: Willumsen, Nicholas, Bager, Cecilie, Karsdal, Morten A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411605/
https://www.ncbi.nlm.nih.gov/pubmed/30856553
http://dx.doi.org/10.1016/j.tranon.2019.02.004