Distinct APE1 Activities Affect the Regulation of VEGF Transcription Under Hypoxic Conditions

Angiogenesis is essential for tumor growth. Vascular endothelial growth factor (VEGF), a crucial factor in tumor angiogenesis, has been reported to be transcriptionally regulated by hypoxia-inducible factor-1 (HIF-1). An 8-oxo-G or apurinic/apyrimidinic (AP) site, which is frequently associated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Mengxia, Dai, Nan, Wang, Dong, Zhong, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411614/
https://www.ncbi.nlm.nih.gov/pubmed/30906512
http://dx.doi.org/10.1016/j.csbj.2019.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411614/
https://www.ncbi.nlm.nih.gov/pubmed/30906512
http://dx.doi.org/10.1016/j.csbj.2019.02.007

Ejemplares similares