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Reduced CD27(−)IgD(−) B Cells in Blood and Raised CD27(−)IgD(−) B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease
The intestinal mucosa in inflammatory bowel disease (IBD) contains increased frequencies of lymphocytes and a disproportionate increase in plasma cells secreting immunoglobulin (Ig)G relative to other isotypes compared to healthy controls. Despite consistent evidence of B lineage cells in the mucosa...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411645/ https://www.ncbi.nlm.nih.gov/pubmed/30891036 http://dx.doi.org/10.3389/fimmu.2019.00361 |