Cargando…
Reduced CD27(−)IgD(−) B Cells in Blood and Raised CD27(−)IgD(−) B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease
The intestinal mucosa in inflammatory bowel disease (IBD) contains increased frequencies of lymphocytes and a disproportionate increase in plasma cells secreting immunoglobulin (Ig)G relative to other isotypes compared to healthy controls. Despite consistent evidence of B lineage cells in the mucosa...
Autores principales: | Pararasa, Chathyan, Zhang, Na, Tull, Thomas J., Chong, Ming H. A., Siu, Jacqueline H. Y., Guesdon, William, Chavele, Konstantia Maria, Sanderson, Jeremy D., Langmead, Louise, Kok, Klaartje, Spencer, Jo, Vossenkamper, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411645/ https://www.ncbi.nlm.nih.gov/pubmed/30891036 http://dx.doi.org/10.3389/fimmu.2019.00361 |
Ejemplares similares
-
Differential Expression of IgM and IgD Discriminates Two Subpopulations of Human Circulating IgM(+)IgD(+)CD27(+) B Cells That Differ Phenotypically, Functionally, and Genetically
por: Bautista, Diana, et al.
Publicado: (2020) -
Impaired CD27(+)IgD(+) B Cells With Altered Gene Signature in Rheumatoid Arthritis
por: Hu, Fanlei, et al.
Publicado: (2018) -
T cell–independent development and induction of somatic hypermutation in human IgM(+)IgD(+)CD27(+) B cells
por: Scheeren, Ferenc A., et al.
Publicado: (2008) -
Expression of IgD by murine lymphocytes. Loss of surface IgD indicates maturation of memory B cells
Publicado: (1978) -
Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM(+)IgD(+)CD27(+) B cell repertoire in infants
por: Weller, Sandra, et al.
Publicado: (2008)