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The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

Some effects of aging in animals are tissue-specific. In D. melanogaster neuronal overexpression of Gclc increases lifespan and improves certain physiological parameters associated with health benefits such as locomotor activity, circadian rhythmicity, and stress resistance. Our previous transcripto...

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Detalles Bibliográficos
Autores principales: Moskalev, Alexey, Guvatova, Zulfiya, Shaposhnikov, Mikhail, Lashmanova, Ekaterina, Proshkina, Ekaterina, Koval, Liubov, Zhavoronkov, Alex, Krasnov, George, Kudryavtseva, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411687/
https://www.ncbi.nlm.nih.gov/pubmed/30891062
http://dx.doi.org/10.3389/fgene.2019.00149