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TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice

While the contribution of Mu Opioid Receptors (MORs) to hedonic aspects of reward processing is well-established, the notion that these receptors may also regulate motivation to gain a reward, and possibly other related cognitive dimensions, has been less investigated. The prefrontal cortex (PFC) is...

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Detalles Bibliográficos
Autores principales: Boulos, Laura-Joy, Nasseef, Md. Taufiq, McNicholas, Michael, Mechling, Anna, Harsan, Laura Adela, Darcq, Emmanuel, Ben Hamida, Sami, Kieffer, Brigitte Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411729/
https://www.ncbi.nlm.nih.gov/pubmed/30858487
http://dx.doi.org/10.1038/s41598-019-40622-6