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ADP-Ribose and oxidative stress activate TRPM8 channel in prostate cancer and kidney cells

Activation of TRPM8 channel through oxidative stress may induce Ca(2+) and pro-apoptotic signals in prostate cancer and kidney cells. The aim of this study was to evaluate activation of TRPM8 can increase apoptosis and oxidative stress in the prostate cancer (Du145(M8)), TRPM8 knock out (Du 145(M8KO...

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Detalles Bibliográficos
Autores principales: Baş, Ercan, Nazıroğlu, Mustafa, Pecze, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411746/
https://www.ncbi.nlm.nih.gov/pubmed/30858386
http://dx.doi.org/10.1038/s41598-018-37552-0