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NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression

N-alpha-acetyltransferase 40 (NAA40) catalyzes the transfer of an acetyl moiety to the alpha-amino group of serine 1 (S1) on histones H4 and H2A. Our previous studies linked NAA40 and its corresponding N-terminal acetylation of histone H4 (N-acH4) to colorectal cancer (CRC). However, the role of NAA...

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Detalles Bibliográficos
Autores principales: Demetriadou, Christina, Pavlou, Demetria, Mpekris, Fotios, Achilleos, Charis, Stylianopoulos, Triantafyllos, Zaravinos, Apostolos, Papageorgis, Panagiotis, Kirmizis, Antonis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411749/
https://www.ncbi.nlm.nih.gov/pubmed/30858358
http://dx.doi.org/10.1038/s41419-019-1487-3