The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages

Inflammation and metabolism are intricately linked during inflammatory diseases in which activation of the nucleotide-binding domain–like receptors Family Pyrin Domain Containing 3 (NLRP3) inflammasome, an innate immune sensor, is critical. Several factors can activate the NLRP3 inflammasome, but th...

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Detalles Bibliográficos
Autores principales: Finucane, Orla M., Sugrue, Jamie, Rubio-Araiz, Ana, Guillot-Sestier, Marie-Victoire, Lynch, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411754/
https://www.ncbi.nlm.nih.gov/pubmed/30858427
http://dx.doi.org/10.1038/s41598-019-40619-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411754/
https://www.ncbi.nlm.nih.gov/pubmed/30858427
http://dx.doi.org/10.1038/s41598-019-40619-1

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