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The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages
Inflammation and metabolism are intricately linked during inflammatory diseases in which activation of the nucleotide-binding domain–like receptors Family Pyrin Domain Containing 3 (NLRP3) inflammasome, an innate immune sensor, is critical. Several factors can activate the NLRP3 inflammasome, but th...
Autores principales: | Finucane, Orla M., Sugrue, Jamie, Rubio-Araiz, Ana, Guillot-Sestier, Marie-Victoire, Lynch, Marina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411754/ https://www.ncbi.nlm.nih.gov/pubmed/30858427 http://dx.doi.org/10.1038/s41598-019-40619-1 |
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