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Molecular architecture of the Jumonji C family histone demethylase KDM5B

The full length human histone 3 lysine 4 demethylase KDM5B (PLU-1/Jarid1B) has been studied using Hydrogen/Deuterium exchange mass spectrometry, homology modelling, sequence analysis, small angle X-ray scattering and electron microscopy. This first structure on an intact multi-domain Jumonji histone...

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Detalles Bibliográficos
Autores principales: Dorosz, Jerzy, Kristensen, Line Hyltoft, Aduri, Nanda G., Mirza, Osman, Lousen, Rikke, Bucciarelli, Saskia, Mehta, Ved, Sellés-Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, Pablo Alcon, Montoya, Guillermo, Nguyen, Tam T. T. N., Rand, Kasper D., Boesen, Thomas, Gajhede, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411775/
https://www.ncbi.nlm.nih.gov/pubmed/30858420
http://dx.doi.org/10.1038/s41598-019-40573-y