Cargando…

Molecular architecture of the Jumonji C family histone demethylase KDM5B

The full length human histone 3 lysine 4 demethylase KDM5B (PLU-1/Jarid1B) has been studied using Hydrogen/Deuterium exchange mass spectrometry, homology modelling, sequence analysis, small angle X-ray scattering and electron microscopy. This first structure on an intact multi-domain Jumonji histone...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dorosz, Jerzy, Kristensen, Line Hyltoft, Aduri, Nanda G., Mirza, Osman, Lousen, Rikke, Bucciarelli, Saskia, Mehta, Ved, Sellés-Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, Pablo Alcon, Montoya, Guillermo, Nguyen, Tam T. T. N., Rand, Kasper D., Boesen, Thomas, Gajhede, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411775/ https://www.ncbi.nlm.nih.gov/pubmed/30858420 http://dx.doi.org/10.1038/s41598-019-40573-y

Ejemplares similares

Jumonji C Demethylases in Cellular Senescence
por: Leon, Kelly E., et al.
Publicado: (2019)

A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36
por: Cheng, Zhongjun, et al.
Publicado: (2014)

Systematic discovery of genetic modulation by Jumonji histone demethylases in Drosophila
por: Shalaby, Nevine A., et al.
Publicado: (2017)

Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival
por: Tran, Tram Anh, et al.
Publicado: (2021)

The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells
por: Zhang, Ziyu, et al.
Publicado: (2021)

Corrigendum: The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells
por: Zhang, Ziyu, et al.
Publicado: (2021)

Cooperation between ETS variant 2 and Jumonji domain-containing 2 histone demethylases
por: Li, Xiaomeng, et al.
Publicado: (2018)

Therapeutic Potentials of Inhibition of Jumonji C Domain-containing Demethylases in Acute Myeloid Leukemia
por: Koca, Duygu, et al.
Publicado: (2020)

Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases
por: Matthews, Krista A., et al.
Publicado: (2020)

Evaluation of Jumonji C lysine demethylase substrate preference to guide identification of in vitro substrates
por: Hoekstra, Matthew, et al.
Publicado: (2022)

Sensitization of Resistant Breast Cancer Cells with a Jumonji Family Histone Demethylase Inhibitor
por: Singh, Balraj, et al.
Publicado: (2022)

Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
por: Leurs, Ulrike, et al.
Publicado: (2014)

KdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans
por: Gacek-Matthews, Agnieszka, et al.
Publicado: (2016)

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase
por: Sinha, Krishna M, et al.
Publicado: (2010)

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
por: Wang, Lei, et al.
Publicado: (2013)

KDM6 Demethylases and Their Roles in Human Cancers
por: Hua, Chunyan, et al.
Publicado: (2021)

Functions and Interactions of Mammalian KDM5 Demethylases
por: Pavlenko, Egor, et al.
Publicado: (2022)

A New Family of Jumonji C Domain-Containing KDM Inhibitors Inspired by Natural Product Purpurogallin
por: Souto, José A., et al.
Publicado: (2020)

KDM6A/B Demethylases in Gut Homeostasis
por: Soshnikova, Natalia
Publicado: (2023)

Involvement of a Jumonji-C domain-containing histone demethylase in DRM2-mediated maintenance of DNA methylation
por: Deleris, Angelique, et al.
Publicado: (2010)

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila
por: Drelon, Coralie, et al.
Publicado: (2018)

The nuclear bodies formed by histone demethylase KDM7A
por: Ming, Hui, et al.
Publicado: (2020)

The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1
por: Camacho, Jessica, et al.
Publicado: (2018)

Stage-Dependent and Locus-Specific Role of Histone Demethylase Jumonji D3 (JMJD3) in the Embryonic Stages of Lung Development
por: Li, Qingtian, et al.
Publicado: (2014)

Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization
por: Ene, Chibawanye I., et al.
Publicado: (2012)

The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor
por: Zheng, Shuzhi, et al.
Publicado: (2019)

JIB-04, a histone demethylase Jumonji C domain inhibitor, regulates phenotypic switching of vascular smooth muscle cells
por: He, Yi, et al.
Publicado: (2022)

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer
por: Blair, Lauren P., et al.
Publicado: (2011)

The histone demethylase Kdm3a is essential to progression through differentiation
por: Herzog, Marielle, et al.
Publicado: (2012)

KDM5 lysine demethylases are involved in maintenance of 3′UTR length
por: Blair, Lauren P., et al.
Publicado: (2016)

Histone demethylase KDM5A promotes tumorigenesis of osteosarcoma tumor
por: Peng, Daohu, et al.
Publicado: (2021)

Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
por: Samanta, Milan Kumar, et al.
Publicado: (2022)

Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression
por: Uribe, Rosa A., et al.
Publicado: (2015)

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells
por: Wu, Liangtang, et al.
Publicado: (2015)

Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells
por: Romani, Massimo, et al.
Publicado: (2019)

Alternative isoforms of KDM2A and KDM2B lysine demethylases negatively regulate canonical Wnt signaling
por: Lađinović, Dijana, et al.
Publicado: (2020)

Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos
por: Glanzner, Werner Giehl, et al.
Publicado: (2020)

KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance
por: Gaillard, Solenne, et al.
Publicado: (2021)

The Lysine Demethylases KdmA and KdmB Differently Regulate Asexual Development, Stress Response, and Virulence in Aspergillus fumigatus
por: Choi, Yong-Ho, et al.
Publicado: (2022)

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
por: Yoo, Jung, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9g3p33fiplqlaqraiinh6nh2av