Cargando…

PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury

Volumetric muscle loss (VML) injury is characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopaedic trauma, that results in chronic functional impairments of the soft tissue. Currently, the effects of VML on the oxidative capacity and adaptability of the rem...

Descripción completa

Detalles Bibliográficos
Autores principales: Southern, William M., Nichenko, Anna S., Tehrani, Kayvan F., McGranahan, Melissa J., Krishnan, Laxminarayanan, Qualls, Anita E., Jenkins, Nathan T., Mortensen, Luke J., Yin, Hang, Yin, Amelia, Guldberg, Robert E., Greising, Sarah M., Call, Jarrod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411870/
https://www.ncbi.nlm.nih.gov/pubmed/30858541
http://dx.doi.org/10.1038/s41598-019-40606-6