USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression

USP18 is an isopeptidase that cleaves the ubiquitin-like ISG15 from conjugates and is also an essential negative feedback regulator of type I interferon signaling. We and others reported that USP18 protein is stabilized by ISG15 and targeted for degradation by SKP2 (S-phase kinase associated protein...

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Detalles Bibliográficos
Autores principales: Vuillier, Françoise, Li, Zhi, Commere, Pierre-Henri, Dynesen, Lasse Toftdal, Pellegrini, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411882/
https://www.ncbi.nlm.nih.gov/pubmed/30858391
http://dx.doi.org/10.1038/s41598-019-39343-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411882/
https://www.ncbi.nlm.nih.gov/pubmed/30858391
http://dx.doi.org/10.1038/s41598-019-39343-7

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