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Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture

Human pancreatic exocrine cells were cultured in 3D suspension and formed pancreatospheres composed of acinar-derived and duct-like cells. We investigated, up to 6 days, the fate of human pancreatic acinar cells using fluorescein-conjugated Ulex Europaeus Agglutinin 1 lectin, a previously published...

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Detalles Bibliográficos
Autores principales: Baldan, Jonathan, Houbracken, Isabelle, Rooman, Ilse, Bouwens, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411888/
https://www.ncbi.nlm.nih.gov/pubmed/30858455
http://dx.doi.org/10.1038/s41598-019-40481-1