Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array

The brain’s extracellular matrix (ECM) is a macromolecular network composed of glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro studies often use purified ECM proteins for cell culture coatings, however these may not represent the molecular complexity and heterogeneit...

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Detalles Bibliográficos
Autores principales: Lam, Doris, Enright, Heather A., Cadena, Jose, Peters, Sandra K. G., Sales, Ana Paula, Osburn, Joanne J., Soscia, David A., Kulp, Kristen S., Wheeler, Elizabeth K., Fischer, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411890/
https://www.ncbi.nlm.nih.gov/pubmed/30858401
http://dx.doi.org/10.1038/s41598-019-40128-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411890/
https://www.ncbi.nlm.nih.gov/pubmed/30858401
http://dx.doi.org/10.1038/s41598-019-40128-1

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