Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association

Polycomb repressive complex 1 (PRC1) is critical for mediating gene repression during development and adult stem cell maintenance. Five CBX proteins, CBX2,4,6,7,8, form mutually exclusive PRC1 complexes and are thought to play a role in the association of PRC1 with chromatin. Specifically, the N-ter...

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Detalles Bibliográficos
Autores principales: Connelly, Katelyn E, Weaver, Tyler M, Alpsoy, Aktan, Gu, Brian X, Musselman, Catherine A, Dykhuizen, Emily C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411926/
https://www.ncbi.nlm.nih.gov/pubmed/30597065
http://dx.doi.org/10.1093/nar/gky1290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411926/
https://www.ncbi.nlm.nih.gov/pubmed/30597065
http://dx.doi.org/10.1093/nar/gky1290

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