DNA polymerase η contributes to genome-wide lagging strand synthesis

DNA polymerase η (pol η) is best known for its ability to bypass UV-induced thymine–thymine (T–T) dimers and other bulky DNA lesions, but pol η also has other cellular roles. Here, we present evidence that pol η competes with DNA polymerases α and δ for the synthesis of the lagging strand genome-wid...

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Detalles Bibliográficos
Autores principales: Kreisel, Katrin, Engqvist, Martin K M, Kalm, Josephine, Thompson, Liam J, Boström, Martin, Navarrete, Clara, McDonald, John P, Larsson, Erik, Woodgate, Roger, Clausen, Anders R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411934/
https://www.ncbi.nlm.nih.gov/pubmed/30597049
http://dx.doi.org/10.1093/nar/gky1291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411934/
https://www.ncbi.nlm.nih.gov/pubmed/30597049
http://dx.doi.org/10.1093/nar/gky1291

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