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Optimization of ribosome profiling using low-input brain tissue from fragile X syndrome model mice

Dysregulated protein synthesis is a major underlying cause of many neurodevelopmental diseases including fragile X syndrome. In order to capture subtle but biologically significant differences in translation in these disorders, a robust technique is required. One powerful tool to study translational...

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Detalles Bibliográficos
Autores principales: Liu, Botao, Molinaro, Gemma, Shu, Huan, Stackpole, Emily E, Huber, Kimberly M, Richter, Joel D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411937/
https://www.ncbi.nlm.nih.gov/pubmed/30590705
http://dx.doi.org/10.1093/nar/gky1292