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Optimization of ribosome profiling using low-input brain tissue from fragile X syndrome model mice
Dysregulated protein synthesis is a major underlying cause of many neurodevelopmental diseases including fragile X syndrome. In order to capture subtle but biologically significant differences in translation in these disorders, a robust technique is required. One powerful tool to study translational...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411937/ https://www.ncbi.nlm.nih.gov/pubmed/30590705 http://dx.doi.org/10.1093/nar/gky1292 |