Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis

PIWI-interacting RNAs (piRNAs) engage PIWI proteins to silence transposons and promote germ cell development in animals. In diverse species, piRNA biogenesis occurs near the mitochondrial surface, and involves mitochondrial membrane-anchored factors. In mice, two cytoplasmic PIWI proteins, MIWI and...

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Detalles Bibliográficos
Autores principales: Ding, Deqiang, Liu, Jiali, Dong, Kunzhe, Melnick, Ashley F, Latham, Keith E, Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411938/
https://www.ncbi.nlm.nih.gov/pubmed/30590800
http://dx.doi.org/10.1093/nar/gky1281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411938/
https://www.ncbi.nlm.nih.gov/pubmed/30590800
http://dx.doi.org/10.1093/nar/gky1281

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