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Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis

PIWI-interacting RNAs (piRNAs) engage PIWI proteins to silence transposons and promote germ cell development in animals. In diverse species, piRNA biogenesis occurs near the mitochondrial surface, and involves mitochondrial membrane-anchored factors. In mice, two cytoplasmic PIWI proteins, MIWI and...

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Detalles Bibliográficos
Autores principales:	Ding, Deqiang, Liu, Jiali, Dong, Kunzhe, Melnick, Ashley F, Latham, Keith E, Chen, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411938/ https://www.ncbi.nlm.nih.gov/pubmed/30590800 http://dx.doi.org/10.1093/nar/gky1281

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