Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays

Androgen receptor (AR) is a ligand-activated transcription factor that plays a pivotal role in the development and progression of many severe diseases such as prostate cancer, muscle atrophy, and osteoporosis. Binding of ligands to AR triggers the conformational changes in AR that may affect the rec...

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Detalles Bibliográficos
Autores principales: Zhou, Wenfang, Duan, Mojie, Fu, Weitao, Pang, Jinping, Tang, Qin, Sun, Huiyong, Xu, Lei, Chang, Shan, Li, Dan, Hou, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411960/
https://www.ncbi.nlm.nih.gov/pubmed/30639122
http://dx.doi.org/10.1016/j.gpb.2018.03.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411960/
https://www.ncbi.nlm.nih.gov/pubmed/30639122
http://dx.doi.org/10.1016/j.gpb.2018.03.007

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