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Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo
Our previous study showed that the oncoprotein SET acts as a new reader of unacetylated p53 for transcriptional repression. To further elucidate the physiological significance of SET in vivo, we generated set knockout mice. Set knockout mice died during embryonic development between day 11.5 and day...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411979/ https://www.ncbi.nlm.nih.gov/pubmed/30858352 http://dx.doi.org/10.1038/s41419-019-1484-6 |