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Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo

Our previous study showed that the oncoprotein SET acts as a new reader of unacetylated p53 for transcriptional repression. To further elucidate the physiological significance of SET in vivo, we generated set knockout mice. Set knockout mice died during embryonic development between day 11.5 and day...

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Detalles Bibliográficos
Autores principales: Kon, Ning, Wang, Donglai, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411979/
https://www.ncbi.nlm.nih.gov/pubmed/30858352
http://dx.doi.org/10.1038/s41419-019-1484-6