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Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis

Hyaluronic acid (HA) is a glycosaminoglycan of extracellular matrix related to cell surface which interacts with various cell types. To understand the role of HA during hepatocarcinogenesis, we assessed the effect of the inhibition of HA deposition and its association with heterogeneous hepatocellul...

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Detalles Bibliográficos
Autores principales: Sukowati, Caecilia H. C., Anfuso, Beatrice, Fiore, Esteban, Ie, Susan I., Raseni, Alan, Vascotto, Fulvia, Avellini, Claudio, Mazzolini, Guillermo, Tiribelli, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411988/
https://www.ncbi.nlm.nih.gov/pubmed/30858465
http://dx.doi.org/10.1038/s41598-019-40436-6