Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer

Hippo pathway is involved in tumorigenesis, and its regulation in cytosol has been extensively studied, but its regulatory mechanisms in the nuclear are not clear. In the current study, using a FBS-inducing model following serum starvation, we identified KDM3A, a demethylase of histone H3K9me1/2, as...

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Detalles Bibliográficos
Autores principales: Wang, Hui-Yi, Long, Qiao-Yun, Tang, Shan-Bo, Xiao, Qiong, Gao, Chuan, Zhao, Quan-Yi, Li, Qing-Lan, Ye, Mei, Zhang, Lei, Li, Lian-Yun, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412006/
https://www.ncbi.nlm.nih.gov/pubmed/30649550
http://dx.doi.org/10.1093/nar/gky1317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412006/
https://www.ncbi.nlm.nih.gov/pubmed/30649550
http://dx.doi.org/10.1093/nar/gky1317

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