Cargando…
Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer
Hippo pathway is involved in tumorigenesis, and its regulation in cytosol has been extensively studied, but its regulatory mechanisms in the nuclear are not clear. In the current study, using a FBS-inducing model following serum starvation, we identified KDM3A, a demethylase of histone H3K9me1/2, as...
Autores principales: | Wang, Hui-Yi, Long, Qiao-Yun, Tang, Shan-Bo, Xiao, Qiong, Gao, Chuan, Zhao, Quan-Yi, Li, Qing-Lan, Ye, Mei, Zhang, Lei, Li, Lian-Yun, Wu, Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412006/ https://www.ncbi.nlm.nih.gov/pubmed/30649550 http://dx.doi.org/10.1093/nar/gky1317 |
Ejemplares similares
-
The histone demethylase Kdm3a is essential to progression through differentiation
por: Herzog, Marielle, et al.
Publicado: (2012) -
Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family
por: Lal, Sneha, et al.
Publicado: (2018) -
The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer
por: Wade, Mark A., et al.
Publicado: (2015) -
The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1
por: Liang, Chung-Yi, et al.
Publicado: (2011) -
Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation
por: Duan, Lingling, et al.
Publicado: (2019)