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Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation

BACKGROUND: Allograft failure is common in lung-transplant recipients and leads to poor outcomes including early death. No reliable clinical tools exist to identify patients at high risk for allograft failure. This study tested the use of donor-derived cell-free DNA (%ddcfDNA) as a sensitive marker...

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Detalles Bibliográficos
Autores principales: Agbor-Enoh, Sean, Wang, Yan, Tunc, Ilker, Jang, Moon Kyoo, Davis, Andrew, De Vlaminck, Iwijn, Luikart, Helen, Shah, Pali D., Timofte, Irina, Brown, Anne W., Marishta, Argit, Bhatti, Kenneth, Gorham, Sasha, Fideli, Ulgen, Wylie, Jennifer, Grimm, David, Goodwin, Natalie, Yang, Yanqin, Patel, Kapil, Zhu, Jun, Iacono, Aldo, Orens, Jonathan B., Nathan, Steven D., Marboe, Charles, Berry, Gerald J., Quake, Stephen R., Khush, Kiran, Valantine, Hannah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412014/
https://www.ncbi.nlm.nih.gov/pubmed/30692045
http://dx.doi.org/10.1016/j.ebiom.2018.12.029