Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone

HSP90 is a ubiquitously expressed molecular chaperone implicated in the correct folding and maturation of a plethora of proteins including protein kinases and transcription factors. While disruption of chaperone activity was associated with augmented cancer cell death and decreased tumor growth both...

Descripción completa

Detalles Bibliográficos
Autores principales: Bekeschus, Sander, Lippert, Maxi, Diepold, Kristina, Chiosis, Gabriela, Seufferlein, Thomas, Azoitei, Ninel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412052/
https://www.ncbi.nlm.nih.gov/pubmed/30858416
http://dx.doi.org/10.1038/s41598-019-38580-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412052/
https://www.ncbi.nlm.nih.gov/pubmed/30858416
http://dx.doi.org/10.1038/s41598-019-38580-0

Ejemplares similares