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Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolism

BACKGROUND: Meningioma is the most frequent primary intracranial tumour. Surgical resection remains the main therapeutic option as pharmacological intervention is hampered by poor knowledge of their proteomic signature. There is an urgent need to identify new therapeutic targets and biomarkers of me...

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Detalles Bibliográficos
Autores principales: Dunn, Jemma, Ferluga, Sara, Sharma, Vikram, Futschik, Matthias, Hilton, David A., Adams, Claire L., Lasonder, Edwin, Hanemann, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412084/
https://www.ncbi.nlm.nih.gov/pubmed/30594554
http://dx.doi.org/10.1016/j.ebiom.2018.12.048