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Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

BACKGROUND: VIS410, a broadly neutralizing monoclonal antibody that binds the hemagglutinin stem of influenza A viruses, was safe and efficacious in a human H1N1 virus challenge study. This study evaluated the safety and tolerability of VIS410 in non-hospitalized adult patients with uncomplicated in...

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Detalles Bibliográficos
Autores principales: Hershberger, Ellie, Sloan, Susan, Narayan, Kristin, Hay, Catherine A., Smith, Patrick, Engler, Frank, Jeeninga, Rienk, Smits, Saskia, Trevejo, Jose, Shriver, Zach, Oldach, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412085/
https://www.ncbi.nlm.nih.gov/pubmed/30638863
http://dx.doi.org/10.1016/j.ebiom.2018.12.051