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Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study
BACKGROUND: VIS410, a broadly neutralizing monoclonal antibody that binds the hemagglutinin stem of influenza A viruses, was safe and efficacious in a human H1N1 virus challenge study. This study evaluated the safety and tolerability of VIS410 in non-hospitalized adult patients with uncomplicated in...
Autores principales: | Hershberger, Ellie, Sloan, Susan, Narayan, Kristin, Hay, Catherine A., Smith, Patrick, Engler, Frank, Jeeninga, Rienk, Smits, Saskia, Trevejo, Jose, Shriver, Zach, Oldach, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412085/ https://www.ncbi.nlm.nih.gov/pubmed/30638863 http://dx.doi.org/10.1016/j.ebiom.2018.12.051 |
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