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Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable in vitro and in vivo Cardiac Optogenetic Models

Adeno-associated viruses (AAVs) provide advantages in long-term, cardiac-specific gene expression. However, AAV serotype specificity data is lacking in experimental models relevant to cardiac electrophysiology and cardiac optogenetics. We aimed to identify the optimal AAV serotype (1, 6, or 9) in pu...

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Detalles Bibliográficos
Autores principales: Ambrosi, Christina M., Sadananda, Gouri, Han, Julie L., Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412093/
https://www.ncbi.nlm.nih.gov/pubmed/30890951
http://dx.doi.org/10.3389/fphys.2019.00168