Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies

P-glycoprotein (P-gp) plays a crucial role in the protection of susceptible organs, by significantly decreasing the absorption/distribution of harmful xenobiotics and, consequently, their toxicity. Therefore, P-gp has been proposed as a potential antidotal pathway, when activated and/or induced. Kno...

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Detalles Bibliográficos
Autores principales: Martins, Eva, Silva, Vera, Lemos, Agostinho, Palmeira, Andreia, Puthongking, Ploenthip, Sousa, Emília, Rocha-Pereira, Carolina, Ghanem, Carolina I., Carmo, Helena, Remião, Fernando, Silva, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412186/
https://www.ncbi.nlm.nih.gov/pubmed/30781374
http://dx.doi.org/10.3390/molecules24040707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412186/
https://www.ncbi.nlm.nih.gov/pubmed/30781374
http://dx.doi.org/10.3390/molecules24040707

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