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Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies

P-glycoprotein (P-gp) plays a crucial role in the protection of susceptible organs, by significantly decreasing the absorption/distribution of harmful xenobiotics and, consequently, their toxicity. Therefore, P-gp has been proposed as a potential antidotal pathway, when activated and/or induced. Kno...

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Detalles Bibliográficos
Autores principales:	Martins, Eva, Silva, Vera, Lemos, Agostinho, Palmeira, Andreia, Puthongking, Ploenthip, Sousa, Emília, Rocha-Pereira, Carolina, Ghanem, Carolina I., Carmo, Helena, Remião, Fernando, Silva, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412186/ https://www.ncbi.nlm.nih.gov/pubmed/30781374 http://dx.doi.org/10.3390/molecules24040707

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