Efficient Synthesis of UDP-Furanoses via 4,5-Dicyanoimidazole(DCI)-Promoted Coupling of Furanosyl-1-Phosphates with Uridine Phosphoropiperidate

A P(V)-N activation method based on nucleoside phosphoropiperidate/DCI system has been developed for improved synthesis of diverse UDP-furanoses. The reaction conditions including temperature, amount of activator, and reaction time were optimized to alleviate the degradation of UDP-furanoses to cycl...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Jie, Han, Shuai-Bo, Xie, Zhen-Biao, Huang, Hua-Shan, Jiang, Duo-Hua, Gong, Shan-Shan, Sun, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412210/
https://www.ncbi.nlm.nih.gov/pubmed/30781738
http://dx.doi.org/10.3390/molecules24040655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412210/
https://www.ncbi.nlm.nih.gov/pubmed/30781738
http://dx.doi.org/10.3390/molecules24040655

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