Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling

A novel banana-shaped molecule using 2,8-Dimethyl-6H,12H-5,11-methanodibenzo [b,f] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh(3))(2)Cl(2) as catalyst, CuI a...

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Autores principales: Yang, Bingchuan, Shen, Guodong, Huang, Xianqiang, Liu, Rutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412220/
https://www.ncbi.nlm.nih.gov/pubmed/30769955
http://dx.doi.org/10.3390/molecules24040698
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author Yang, Bingchuan
Shen, Guodong
Huang, Xianqiang
Liu, Rutao
author_facet Yang, Bingchuan
Shen, Guodong
Huang, Xianqiang
Liu, Rutao
author_sort Yang, Bingchuan
collection PubMed
description A novel banana-shaped molecule using 2,8-Dimethyl-6H,12H-5,11-methanodibenzo [b,f] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh(3))(2)Cl(2) as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by (1)H-NMR, (13)C-NMR, Fourier transform infrared (FT-IR) spectroscopy and mass spectrometry.
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spelling pubmed-64122202019-04-09 Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling Yang, Bingchuan Shen, Guodong Huang, Xianqiang Liu, Rutao Molecules Article A novel banana-shaped molecule using 2,8-Dimethyl-6H,12H-5,11-methanodibenzo [b,f] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh(3))(2)Cl(2) as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by (1)H-NMR, (13)C-NMR, Fourier transform infrared (FT-IR) spectroscopy and mass spectrometry. MDPI 2019-02-15 /pmc/articles/PMC6412220/ /pubmed/30769955 http://dx.doi.org/10.3390/molecules24040698 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Bingchuan
Shen, Guodong
Huang, Xianqiang
Liu, Rutao
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title_full Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title_fullStr Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title_full_unstemmed Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title_short Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
title_sort design and synthesis of a novel banana-shaped functional molecule via double cross-coupling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412220/
https://www.ncbi.nlm.nih.gov/pubmed/30769955
http://dx.doi.org/10.3390/molecules24040698
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AT shenguodong designandsynthesisofanovelbananashapedfunctionalmoleculeviadoublecrosscoupling
AT huangxianqiang designandsynthesisofanovelbananashapedfunctionalmoleculeviadoublecrosscoupling
AT liurutao designandsynthesisofanovelbananashapedfunctionalmoleculeviadoublecrosscoupling

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