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Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives

A new series of glycyrrhetinic acid derivatives has been synthesized via the introduction of different heterocyclic rings conjugated with an α,β-unsaturated ketone in its ring A. These new compounds were screened for their antiproliferative activity in a panel of nine human cancer cell lines. Compou...

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Detalles Bibliográficos
Autores principales: Alho, Daniela P. S., Salvador, Jorge A. R., Cascante, Marta, Marin, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412232/
https://www.ncbi.nlm.nih.gov/pubmed/30791593
http://dx.doi.org/10.3390/molecules24040766