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Ergosterol Ameliorates Diabetic Nephropathy by Attenuating Mesangial Cell Proliferation and Extracellular Matrix Deposition via the TGF-β1/Smad2 Signaling Pathway

(1) Background: Diabetic nephropathy, a microvascular complication of diabetes, is one of the principal causes of end-stage renal disease worldwide. The aim of this study was to explore the therapeutic effects of ergosterol on diabetic nephropathy. (2) Methods: Streptozotocin (STZ)-induced C57BL/6 d...

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Detalles Bibliográficos
Autores principales: Dong, Zhonghua, Sun, Yueyue, Wei, Guangwei, Li, Siying, Zhao, Zhongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412245/
https://www.ncbi.nlm.nih.gov/pubmed/30823598
http://dx.doi.org/10.3390/nu11020483