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Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor highly expressed in hepatocytes. Researchers have employed global and liver-specific conditional Ahr knockout mouse models to characterize the physiological roles of the AHR; however, the gestational timing of AHR loss in...

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Detalles Bibliográficos
Autores principales: Girer, Nathaniel G., Carter, Dwayne, Bhattarai, Nisha, Mustafa, Mehnaz, Denner, Larry, Porter, Craig, Elferink, Cornelis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412252/
https://www.ncbi.nlm.nih.gov/pubmed/30813227
http://dx.doi.org/10.3390/ijms20040950