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Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor highly expressed in hepatocytes. Researchers have employed global and liver-specific conditional Ahr knockout mouse models to characterize the physiological roles of the AHR; however, the gestational timing of AHR loss in...
Autores principales: | Girer, Nathaniel G., Carter, Dwayne, Bhattarai, Nisha, Mustafa, Mehnaz, Denner, Larry, Porter, Craig, Elferink, Cornelis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412252/ https://www.ncbi.nlm.nih.gov/pubmed/30813227 http://dx.doi.org/10.3390/ijms20040950 |
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